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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1976-1982
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1976
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1976
Diabetes insipidus with impaired vision caused by germinoma and perioptic meningeal seeding: A case report
Na Yang, Hui-Juan Zhu, Li-Yun He, Yu-Xiu Li, Hua-Bing Zhang, Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Yong Yao, Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Hui You, Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Author contributions: Zhang HB, Zhu HJ, Yao Y, and Yang N treated the patient; Zhang HB and Yang N collected the data and drafted the manuscript; Yang N and He LY participated in the analysis; Zhang HB, Zhu HJ, Yao Y, You H, and Li YX critically revised the manuscript; all authors have approved the final article.
Supported by Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences , No. 2019XK320029 ; National Natural Science Foundation of China , No. 91846106 ; and Education and Teaching Reform Project of Peking Union Medical College , No. 2014zlgc0316 .
Informed consent statement: Written informed consent was obtained from the patient and her parent for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hua-Bing Zhang, MD, Associate Professor, Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. huabingzhangchn@163.com
Received: November 18, 2020
Peer-review started: November 18, 2020
First decision: December 3, 2020
Revised: December 12, 2020
Accepted: January 8, 2021
Article in press: January 8, 2021
Published online: March 16, 2021
Processing time: 106 Days and 0.2 Hours
Peer-review started: November 18, 2020
First decision: December 3, 2020
Revised: December 12, 2020
Accepted: January 8, 2021
Article in press: January 8, 2021
Published online: March 16, 2021
Processing time: 106 Days and 0.2 Hours
Core Tip
Core Tip: Impaired vision is one of the clinical manifestations of a germinoma, and most of the reduction in visual acuity is caused by compression of the optic chiasma. We present a case of impaired vision caused by a germinoma and perioptic meningeal seeding, which is extremely rare. The findings of this case study emphasize that children with diabetes insipidus need a complete differential diagnosis.