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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1901-1908
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1901
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1901
Severe community-acquired pneumonia caused by Leptospira interrogans: A case report and review of literature
Qiu-Hong Bao, Jian-Ming Pang, Department of Respiratory and Critical Medicine, Tiantai Hospital of Hangzhou Medical College, Tiantai 317200, Zhejiang Province, China
Li Yu, Ying-Jun Chen, Jun-Wei Wang, Department of Infectious Disease, Tiantai Hospital of Hangzhou Medical College, Tiantai 317200, Zhejiang Province, China
Jian-Jun Ding, Department of Critical Care Medicine, Tiantai Hospital of Hangzhou Medical College, Tiantai 317200, Zhejiang Province, China
Qi Jin, ICU Administration, Tiantai Hospital of Hangzhou Medical College, Taizhou 317200, Zhejiang Province, China
Author contributions: Bao QH and Jin Q contributed to conception and design, manuscript writing and final approval of the manuscript; Wang JW and Pang JM performed the research; Chen YJ provided financial support and manuscript writing; Ding JJ and Yu L analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Supported by Basic Public Welfare Research Scheme of Zhejiang Province , No. GF19H030001 .
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qi Jin, MD, Chief Physician, ICU Administration, Tiantai Hospital of Hangzhou Medical College, No. 1 Middle Corning Road, Shifeng Street, Taizhou 317200, Zhejiang Province, China. 991044@sina.com
Received: October 15, 2020
Peer-review started: October 15, 2020
First decision: December 13, 2020
Revised: December 24, 2020
Accepted: January 28, 2021
Article in press: January 28, 2021
Published online: March 16, 2021
Peer-review started: October 15, 2020
First decision: December 13, 2020
Revised: December 24, 2020
Accepted: January 28, 2021
Article in press: January 28, 2021
Published online: March 16, 2021
Core Tip
Core Tip: Pneumonia caused by Leptospira interrogans is rare but life-threatening. In the early phase, the nonspecific symptoms of Leptospira pneumonia often lead clinicians to misdiagnosis as influenza or other illness. We herein report a 54-year-old man who presented with cough, fever and dyspnea and was misdiagnosed with influenza but was confirmed with Leptospira infection with the help of next generation sequencing. Possible exposure history and next generation sequencing during management of infections with unknown causes are important.