Observational Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1827-1834
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1827
Bedside cardiopulmonary ultrasonography evaluates lung water content in very low-weight preterm neonates with patent ductus arteriosus
Li-Fang Yu, Chen-Ke Xu, Min Zhao, Lin Niu, Xian-Mei Huang, Zhi-Qun Zhang
Li-Fang Yu, Chen-Ke Xu, Min Zhao, Lin Niu, Department of Ultrasound, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Xian-Mei Huang, Zhi-Qun Zhang, Department of Pediatrics, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Author contributions: Zhao M, Huang XM and Zhang ZQ designed the research; Niu L and Zhao M performed the research; Yu LF and Xu CK collected and analyzed the data; Yu LF, Xu CK and Zhao M wrote the paper.
Supported by Zhejiang Medical and Health Science and Technology Project, No. 2020ky690; and Zhejiang Natural Science Public Welfare Fund, No. LGF20H020004.
Institutional review board statement: This study was approved by the ethics committee of Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Zhao, MD, Department of Ultrasound, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, No. 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China. hzzhaomin@126.com
Received: December 1, 2020
Peer-review started: December 1, 2020
First decision: December 24, 2020
Revised: January 6, 2021
Accepted: January 25, 2021
Article in press: January 25, 2021
Published online: March 16, 2021
Core Tip

Core Tip: Patent ductus arteriosus (PDA) has a high incidence in very low-weight preterm neonates. If PDA persists, then interstitial lung water content increases, which could cause hemodynamic changes and pulmonary edema. Thus, early and reliable assessment of lung water content is important in these cases. In this study, we performed cardiopulmonary ultrasonography on the fourth day after birth to investigate whether there are differences between neonates with or without PDA. The results indicated that neonates with PDA had higher lung water content. Lung ultrasonography score had moderate accuracy for predicting the possibility of hemodynamic changes in persistent PDA.