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World J Clin Cases. Feb 6, 2021; 9(4): 801-811
Published online Feb 6, 2021. doi: 10.12998/wjcc.v9.i4.801
Biliary stent combined with iodine-125 seed strand implantation in malignant obstructive jaundice
Hui-Wen Wang, Xiao-Jing Li, Shi-Jie Li, Jun-Rong Lu, Dong-Feng He
Hui-Wen Wang, Xiao-Jing Li, Shi-Jie Li, Jun-Rong Lu, Dong-Feng He, Department of Interventional, Harbin Medical University Cancer Hospital, Harbin 150081, Heilongjiang Province, China
Author contributions: Wang HW and Li XJ drafted the manuscript and analyzed all the data; He DF performed the surgeries and acquired data; Li SJ and Lu JR assisted in all surgeries and data collection; He DF designed and supervised the study, analyzed all the data, and revised the manuscript.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Review Committee of Harbin Medical University Cancer Hospital.
Clinical trial registration statement: This registration policy applies to prospective, randomized, controlled trials only.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no competing interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dong-Feng He, PhD, Research Scientist, Surgical Oncologist, Department of Interventional, Harbin Medical University Cancer Hospital, No. 150 Haping Street, Nangang District, Harbin 150081, Heilongjiang Province, China. 13644578588@139.com
Received: November 3, 2020
Peer-review started: November 3, 2020
First decision: November 20, 2020
Revised: November 23, 2020
Accepted: December 10, 2020
Article in press: December 10, 2020
Published online: February 6, 2021
Processing time: 83 Days and 9.7 Hours
Core Tip

Core Tip: For patients who are unable to undergo surgery, biliary stent placement can relieve biliary obstruction and prolong survival. However, previous studies relieved stenosis caused by an existing tumor lesion by placing an iodine-125 seed in the middle of the stent while ignoring both ends. Both ends of the stent can be reobstructed. We observed that extending the iodine-125 seed strand along the length of the stent produced a safe and effective result in malignant obstructive jaundice.