Minireviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2021; 9(33): 10064-10074
Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10064
Effects of anti-diabetic drugs on sarcopenia: Best treatment options for elderly patients with type 2 diabetes mellitus and sarcopenia
Xiao-Yu Ma, Fen-Qin Chen
Xiao-Yu Ma, Fen-Qin Chen, Department of Geriatrics, The First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: All authors met the criteria for authorship; Ma XY was responsible for drafting the manuscript; Chen FQ was responsible for the concept of the study and reviewed and edited the manuscript.
Supported by National Natural Science Foundation of China, No. 81600693.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fen-Qin Chen, Doctor, MD, PhD, Associate Professor, Department of Geriatrics, The First Affiliated Hospital, China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110001, Liaoning Province, China. chenfenqin7881@163.com
Received: July 14, 2021
Peer-review started: July 14, 2021
First decision: August 8, 2021
Revised: August 22, 2021
Accepted: September 30, 2021
Article in press: September 30, 2021
Published online: November 26, 2021
Processing time: 130 Days and 21.6 Hours
Core Tip

Core Tip: Elderly patients with diabetes are at an increased risk for sarcopenia. Therefore, these older diabetic patients with sarcopenia need specific anti-diabetic therapies targeting not only glycemic control but also sarcopenia, with the goal of preventing sarcopenia in pre-sarcopenic patients. We herein discuss the association between diabetes and sarcopenia in geriatric patients, and how anti-diabetic drugs may influence sarcopenia outcomes.