Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2021; 9(31): 9607-9616
Published online Nov 6, 2021. doi: 10.12998/wjcc.v9.i31.9607
T-cell lymphoblastic lymphoma with extensive thrombi and cardiac thrombosis: A case report and review of literature
Ying-Ying Ma, Quan-Chao Zhang, Xu Tan, Xi Zhang, Cheng Zhang
Ying-Ying Ma, Xu Tan, Xi Zhang, Cheng Zhang, Department of Hematology, State Key Laboratory of Trauma, Burns and Combined Injury, Xinqiao Hospital of Army Medical University, Chongqing 400037, China
Quan-Chao Zhang, Department of Nephrology, The Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China
Author contributions: Ma YY and Zhang QC drafted the manuscript and prepared the figures; Zhang C and Zhang X developed the treatment regimens and reviewed the manuscript; Zhang X aided in the literature search and provided support in the literature discussion; All authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this Case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cheng Zhang, PhD, Doctor, Department of Hematology, State Key Laboratory of Trauma, Burns and Combined Injury, Xinqiao Hospital of Army Medical University, No. 83 Xinqiaozheng Street, Shapingba District, Chongqing 400037, China. chzhang2014@163.com
Received: April 29, 2021
Peer-review started: April 29, 2021
First decision: July 15, 2021
Revised: July 28, 2021
Accepted: September 10, 2021
Article in press: September 10, 2021
Published online: November 6, 2021
Processing time: 183 Days and 3.6 Hours
Core Tip

Core Tip: T-lymphoblastic lymphoma (T-LBL), a neoplasm of immature T-cell precursors or lymphoblasts, is a clinically aggressive disease. We present herein, a rare case of T-cell lymphoblastic lymphoma with extensive thrombi and cardiac thrombosis. This case highlights the ultimate importance of monitoring changes in embolus size and whether the embolus falls off during the treatment to avoid potentially serious multi-organ thrombosis complications. In addition, this case also confirmed that pegylated liposomal doxorubicin and chidamide are safe and effective in the treatment of T-LBL/leukemia.