Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2021; 9(30): 9144-9150
Published online Oct 26, 2021. doi: 10.12998/wjcc.v9.i30.9144
Synchronous diagnosis and treatment of acute myeloid leukemia and chronic lymphocytic leukemia: Two case reports
Rong-Rong Chen, Li-Xia Zhu, Lu-Lu Wang, Xue-Ying Li, Jia-Nai Sun, Mi-Xue Xie, Jing-Jing Zhu, De Zhou, Jian-Hu Li, Xin Huang, Wan-Zhuo Xie, Xiu-Jin Ye
Rong-Rong Chen, Li-Xia Zhu, Lu-Lu Wang, Xue-Ying Li, Jia-Nai Sun, Mi-Xue Xie, Jing-Jing Zhu, De Zhou, Jian-Hu Li, Xin Huang, Wan-Zhuo Xie, Xiu-Jin Ye, Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Chen RR collected the patient’s clinical data, reviewed the literature, and drafted the manuscript; Zhu LX was the patients’ physician; Wang LL were involved in case analysis and treatment discussion; Ye XJ contributed to the drafting and revision of the manuscript; all authors issued final approval of the version to be submitted.
Informed consent statement: Consent was obtained from relatives of the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiu-Jin Ye, PhD, Chief Doctor, Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. yxjsunny@zju.edu.cn
Received: March 28, 2021
Peer-review started: March 28, 2021
First decision: July 8, 2021
Revised: July 13, 2021
Accepted: September 3, 2021
Article in press: September 3, 2021
Published online: October 26, 2021
Core Tip

Core Tip: The concurrence of acute myeloid leukemia (AML) and chronic lymphocytic leukemia is rare, and patients with both diseases have a poor prognosis. The clinical features, include male predominance and a predilection for older patients, and the AML-M2 subtype is the most frequent subtype. Infection and rapid progression are the most common causes of death in these patients.