Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2021; 9(30): 8953-8966
Published online Oct 26, 2021. doi: 10.12998/wjcc.v9.i30.8953
Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions
Sen-Tong Xiao, Chun-Yan Kuang
Sen-Tong Xiao, Department of Cardiovascular Diseases, People’s Hospital Affiliated to Guizhou Medical University, Guiyang 550003, Guizhou Province, China
Chun-Yan Kuang, Department of Cardiovascular Diseases, Guizhou Provincial People's Hospital, Guiyang 550003, Guizhou Province, China
Author contributions: Xiao ST wrote the manuscript; Kuang CY revised the article.
Supported by the Guizhou Science and Technology Department, No. Qian-Ke-He [2018]1097; the National Natural Science Foundation of China, No. 81560056; Program for Training Outstanding Young Scientific and Technological Talents of Guizhou Province, No. Qian Kehe Platform Talents [2019]5662; Program for the Scientific Activities of Selected Returned Overseas Professionals in Guizhou Province, No. Grant Qian-Ren [2018]0003; and Scientific and Technological Platform and Talent Team Project of Guizhou Province, No. Qian Kehe Platform Talents [2017]5405.
Conflict-of-interest statement: The authors report that they have no conflicting interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Yan Kuang, MD, PhD, Chief Physician, Department of Cardiovascular Diseases, Guizhou Provincial People's Hospital, No. 83 Zhongshan East Road, Guiyang 550003, Guizhou Province, China. xiaokcy@sina.com
Received: March 26, 2021
Peer-review started: March 26, 2021
First decision: May 12, 2021
Revised: May 12, 2021
Accepted: August 18, 2021
Article in press: August 18, 2021
Published online: October 26, 2021
Core Tip

Core Tip: The development of clinical applications of endothelial progenitor cells (EPCs) has progressed in recent decades. In this review, we summarize and discuss the origins and antibody markers of EPCs and the clinical effects of EPC stents and infusion. We hope to predict future clinical uses of EPCs.