Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 16, 2021; 9(29): 8894-8900
Published online Oct 16, 2021. doi: 10.12998/wjcc.v9.i29.8894
Ovarian pregnancy rupture following ovulation induction and intrauterine insemination: A case report
Bin Wu, Ke Li, Xiao-Fen Chen, Jie Zhang, Jing Wang, Yue Xiang, Hong-Gui Zhou
Bin Wu, Ke Li, Xiao-Fen Chen, Jie Zhang, Jing Wang, Hong-Gui Zhou, Reproductive Medicine Centre, Department of Obstetrics and Gynecology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Bin Wu, Hong-Gui Zhou, Non-invasive and Microinvasive Laboratory of Gynecology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Yue Xiang, Department of Pathology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Author contributions: Wu B designed, performed the study, and wrote the manuscript; Wu B, Li K, Chen XF, and Zhou HG performed the ovulation induction and intrauterine insemination; Li Kand Zhou HGperformed the laparoscopic surgery; Zhang J and Wang J searched all the cases and conducted the analysis; Xiang Y performed the pathologic analysis; All authors read and approved the final manuscript for publication.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist(2016), and the manuscript was prepared and revised accordingly.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Gui Zhou, MS, Doctor, Reproductive Medicine Centre, Department of Obstetrics and Gynecology, The Affiliated Hospital of North Sichuan Medical College, No. 1Maoyuan South Road, Nanchong 637000, Sichuan Province, China. 492942672@qq.com
Received: June 8, 2021
Peer-review started: June 8, 2021
First decision: June 25, 2021
Revised: July 7, 2021
Accepted: July 28, 2021
Article in press: July 28, 2021
Published online: October 16, 2021
Processing time: 129 Days and 6.6 Hours
Core Tip

Core Tip: Ovarian pregnancy following intrauterine insemination (IUI) is a rare complication with few case reports; ovarian enlargement due to ovulation induction increases the risk of ovarian rupture, causing severe bleeding. Close attention should be paid to patients with a history of pelvic inflammatory disease before commencing IUI treatment,and such patients should be closely followed up after IUI. Early measurement of serumβ-human chorionic gonadotropin levels and ultrasonic examination could facilitate a timely diagnosis of ovarian pregnancy rupture after ovulation induction and IUI.