Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 16, 2021; 9(29): 8864-8870
Published online Oct 16, 2021. doi: 10.12998/wjcc.v9.i29.8864
Adenomyoepithelioma of the breast with malignant transformation and repeated local recurrence: A case report
Goshi Oda, Tsuyoshi Nakagawa, Mio Mori, Tomoyuki Fujioka, Iichiro Onishi
Goshi Oda, Tsuyoshi Nakagawa, Department of Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8519, Japan
Mio Mori, Tomoyuki Fujioka, Department of Radiology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan
Iichiro Onishi, Department of Pathology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan
Author contributions: Goshi O performed surgery, and wrote the manuscript; Tsuyoshi N performed surgery and collected data; Mio M and Tomoyuki F were responsible for diagnostic imaging and ultrasound-guided needle biopsy; Iichiro O was in charge of the pathology; all authors read and approved the final version.
Informed consent statement: Written and signed informed consent for publication of this case was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tsuyoshi Nakagawa, MD, PhD, Doctor, Department of Breast Surgery, Tokyo Medical and Dental University, Yushima 1-5-45, Bunnkyo-ku, Tokyo 113-8519, Japan. dgsh197877@hotmail.com
Received: May 31, 2021
Peer-review started: May 31, 2021
First decision: June 24, 2021
Revised: July 5, 2021
Accepted: August 23, 2021
Article in press: August 23, 2021
Published online: October 16, 2021
Core Tip

Core Tip: Adenomyoepithelioma (AME) of the breast is a very rare type of benign tumor of the breast. Many AMEs demonstrate benign behavior and are often cured with excision with negative margins, but some AMEs exhibit malignant transformation of the myoepithelium, glandular epithelium, or both. We report the case of a patient with AME with repeated local recurrences and malignant transformation.