Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2021; 9(23): 6798-6803
Published online Aug 16, 2021. doi: 10.12998/wjcc.v9.i23.6798
Psoriasis treatment using minimally manipulated umbilical cord-derived mesenchymal stem cells: A case report
Hyunjun Ahn, Sang Yeon Lee, Won-Ju Jung, Jia Pi, Kye-Ho Lee
Hyunjun Ahn, Sang Yeon Lee, Jia Pi, Kye-Ho Lee, bio Beauty&Health Company (bBHC)-Stem Cell Treatment and Research Institute (STRI), Seoul 04420, South Korea
Hyunjun Ahn, Department of Functional Genomics, University of Science and Technology KRIBB School, Deajeon 34113, South Korea
Won-Ju Jung, Stem Cell Treatment, 97.7 B&H Clinic, Seoul 04420, South Korea
Author contributions: Ahn H, Lee SY, Jung WJ and Lee KH designed the reports; Ahn H, Pi J and Jung WJ collected the patient’s clinical data; Ahn H, Pi J and Jung WJ analyzed the data; Ahn H and Pi J wrote the manuscript; Lee KH provided professional advice and revised the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: The patient involved in this study gave his written informed consent authorizing disclosure of his protected health information.
Conflict-of-interest statement: All authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kye-Ho Lee, PhD, Stem Cell Rearch, STRI, 72 UNvillage-gil Yongsan-gu, Seoul 04420, South Korea. sylee@stc365.com
Received: January 13, 2021
Peer-review started: January 13, 2021
First decision: May 11, 2021
Revised: May 24, 2021
Accepted: July 6, 2021
Article in press: July 6, 2021
Published online: August 16, 2021
Core Tip

Core Tip: In recent decades, interest in biomedical applications of mesenchymal stem cells (MSCs) has increased due to their anti-inflammatory, immunosuppressive, and immunomodulatory abilities. MSCs have been used to study a variety of human diseases without side effects. The human umbilical cord is an excellent source of MSCs. We sought to improve a patient’s psoriatic condition by using minimally manipulated umbilical cord-derived MSCs. In this case study, we report the efficacy of the minimally manipulated umbilical cord-derived MSC therapy to treat a patient with psoriasis.