Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2021; 9(22): 6544-6551
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6544
Management of an intracranial hypotension patient with diplopia as the primary symptom: A case report
Ting-Ting Wei, Hua Huang, Gang Chen, Fei-Fang He
Ting-Ting Wei, Gang Chen, Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Hua Huang, Fei-Fang He, Department of Pain Management, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Wei TT and Chen G reviewed the literature and contributed to manuscript drafting; Huang H and He FF analyzed, interpreted the imaging findings, and drafted the manuscript; Wei TT, Huang H, He FF, and Chen G were responsible for the revision of the manuscript for important intellectual content; All authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that there is no conflict of interest in this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gang Chen, PhD, Chief Doctor, Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, No. 3 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. chengang120@zju.edu.cn
Received: April 11, 2021
Peer-review started: April 20, 2021
First decision: May 11, 2021
Revised: May 18, 2021
Accepted: May 26, 2021
Article in press: May 26, 2021
Published online: August 6, 2021
Processing time: 107 Days and 12 Hours
Core Tip

Core Tip: Intracranial hypotension (IH) is an uncommon disorder of cerebrospinal fluid (CSF) hypovolemia due to spontaneous or iatrogenic spinal CSF leakage, and is easily being misdiagnosed or missed as it can be associated with a large diversity of clinical signs. To the best of our knowledge, this is the first case in the literature describing a patient of having IH with diplopia as his initial and primary complaint, and demonstrating the efficacy of repeated epidural blood patch therapy in managing a patient with multiple sites of CSF leakage in the spine complicated with cranial nerve VI injury and subdural hematomas.