Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2021; 9(22): 6435-6442
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6435
Manifestation of severe pneumonia in anti-PL-7 antisynthetase syndrome and B cell lymphoma: A case report
Xuan-Li Xu, Ru-Hui Zhang, Yue-Hong Wang, Jian-Ying Zhou
Xuan-Li Xu, Ru-Hui Zhang, Yue-Hong Wang, Jian-Ying Zhou, Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Author contributions: Xu XL and Zhang RH were the patient’s physician, reviewed the literature and contributed to manuscript drafting; Wang YH and Zhou JY were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported by National Natural Science Foundation of China, No. 81900020; and Natural Science Foundation of Zhejiang Province, China, No. LQ19H160020.
Informed consent statement: Study participant and his legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Ying Zhou, MD, Chief Doctor, Professor, Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 9 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zjyhz@zju.edu.cn
Received: April 3, 2021
Peer-review started: April 3, 2021
First decision: April 28, 2021
Revised: May 8, 2021
Accepted: May 24, 2021
Article in press: May 24, 2021
Published online: August 6, 2021
Core Tip

Core Tip: Antisynthetase syndrome (ASS) is a unique subset of inflammatory myopathy. Patients with inflammatory myopathies carry a higher risk of developing neoplasms, most commonly adenocarcinoma but not lymphoma or other hematologic neoplasms. However, data on the association between ASS and malignancy remain very scant. We present here a rare case of severe pneumonia and acute hypoxemic respiratory failure as the first indicator for anti-PL-7 ASS accompanied by B cell lymphoma.