Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2021; 9(22): 6388-6392
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6388
Prostatic carcinosarcoma seven years after radical prostatectomy and hormonal therapy for prostatic adenocarcinoma: A case report
Xiao Huang, Song-Liang Cai, Li-Ping Xie
Xiao Huang, Song-Liang Cai, Li-Ping Xie, Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310030, Zhejiang Province, China
Author contributions: Huang X analyzed the data and wrote the manuscript; Cai SL performed the surgery and collected the data; Xie LP contributed to manuscript reviewing; all authors have read and approved the final manuscript.
Supported by the Natural Science Foundation of Zhejiang Province, China, No. LY19H050008.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao Huang, MD, PhD, Chief Doctor, Professor, Surgeon, Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310030, Zhejiang Province, China. xiaohuang69@zju.edu.cn
Received: January 10, 2021
Peer-review started: January 10, 2021
First decision: February 11, 2021
Revised: February 28, 2021
Accepted: June 16, 2021
Article in press: June 16, 2021
Published online: August 6, 2021
Processing time: 198 Days and 10.4 Hours
Core Tip

Core Tip: This is an unusual case of delayed occurrence of prostatic carcinosarcoma 7 years after radical prostatectomy and androgen deprivation therapy (ADT) for prostatic adenocarcinoma. It is very uncommon for a patient to have both neoplasms. ADT mediated transformation and dedifferentiation of the epithelial component may be the origin of this malignancy.