Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2021; 9(22): 6287-6299
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6287
Diagnostic and prognostic value of secreted protein acidic and rich in cysteine in the diffuse large B-cell lymphoma
Peng-Ji Pan, Jun-Xia Liu
Peng-Ji Pan, Department of Hematology, Yongchuan Hospital of Chongqing Medical University, Chongqing 402160, China
Jun-Xia Liu, Department of Oncology, Yongchuan Hospital of Chongqing Medical University, Chongqing 402160, China
Author contributions: Pan PJ conducted the experimental analysis and wrote the manuscript; Liu JX performed the statistical analysis and revised the manuscript; all authors read and approved the final version of the manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of the Yongchuan Hospital of Chongqing Medical University.
Informed consent statement: Patients were not required to give informed consent to this study because the analysis used anonymous data from a database.
Conflict-of-interest statement: All authors have no conflict of interests to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun-Xia Liu, MD, Chief Doctor, Department of Oncology, Yongchuan Hospital of Chongqing Medical University, No. 439 Xuanhua Road, Yongchuan District, Chongqing 402160, China. bepooo@aliyun.com
Received: April 25, 2021
Peer-review started: April 25, 2021
First decision: May 24, 2021
Revised: May 29, 2021
Accepted: June 3, 2021
Article in press: June 3, 2021
Published online: August 6, 2021
Processing time: 93 Days and 13.3 Hours
Core Tip

Core Tip: In this study, the expression and significance of secreted protein acidic and rich in cysteine (SPARC) in the diffuse large B-cell lymphoma (DLBCL) were evaluated. The overexpression of SPARC can be an efficient diagnostic and prognostic biomarker for DLBCL, suggesting that SPARC has a potential value in future clinical application.