Luquez-Mindiola A, Atuesta AJ, Gómez-Aldana AJ. Gastrointestinal manifestations of systemic sclerosis: An updated review. World J Clin Cases 2021; 9(22): 6201-6217 [PMID: 34434988 DOI: 10.12998/wjcc.v9.i22.6201]
Corresponding Author of This Article
Andres Jose Gómez-Aldana, MD, Attending Doctor, Department of Endoscopy, Santa Fe Foundation of Bogotá (Fundación Santa Fe de Bogotá), Cra 7 # 117 15, Bogotá 11711, Colombia. andresgomezmd@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 6, 2021; 9(22): 6201-6217 Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6201
Gastrointestinal manifestations of systemic sclerosis: An updated review
Adan Luquez-Mindiola, Alexis Javier Atuesta, Andres Jose Gómez-Aldana
Adan Luquez-Mindiola, Department of Gastroenterology, Gut Médica, Bogota 11711 Colombia
Alexis Javier Atuesta, Department of Internal Medicine, Universidad Nacional de Colombia, Bogota 11711, Colombia
Andres Jose Gómez-Aldana, Department of Endoscopy, Santa Fe Foundation of Bogotá (Fundación Santa Fe de Bogotá), Bogotá 11711, Colombia
Andres Jose Gómez-Aldana, Faculty of Medicine, Universidad de los Andes, Bogota 11711, Colombia
Author contributions: Luquez-Mindiola A was involved in the study conceptualization, and manuscript edition and writing; Atuesta AJ was involved in manuscript writing and study conceptualization; and Gómez-Aldana AJ was involved in study conceptualization, and writing and editing of the manuscript.
Conflict-of-interest statement: The authors have nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andres Jose Gómez-Aldana, MD, Attending Doctor, Department of Endoscopy, Santa Fe Foundation of Bogotá (Fundación Santa Fe de Bogotá), Cra 7 # 117 15, Bogotá 11711, Colombia. andresgomezmd@hotmail.com
Received: January 18, 2021 Peer-review started: January 18, 2021 First decision: February 9, 2021 Revised: March 30, 2021 Accepted: June 7, 2021 Article in press: June 7, 2021 Published online: August 6, 2021
Core Tip
Core Tip: Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis of the skin, and internal organ dysfunction. Gastrointestinal involvement is the most common complication of internal organs, impacting up to 90% of patients. This involvement can affect any region of the gastrointestinal tract from the mouth to the anus, with a predominance of alterations being observed in the upper digestive tract. The gastrointestinal involvement primarily involves the esophagus, small intestine, and rectum. The severity of gastrointestinal involvement affects quality of life and is a marker of worse prognosis and mortality in these patients. In this review, we describe the current findings regarding gastrointestinal involvement by this entity.
