Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2021; 9(21): 6155-6169
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.6155
Complicated course of biliary inflammatory myofibroblastic tumor mimicking hilar cholangiocarcinoma: A case report and literature review
Sandra Strainiene, Kotryna Sedleckaite, Juozas Jarasunas, Ilona Savlan, Juozas Stanaitis, Ieva Stundiene, Tomas Strainys, Valentina Liakina, Jonas Valantinas
Sandra Strainiene, Ilona Savlan, Juozas Stanaitis, Ieva Stundiene, Valentina Liakina, Jonas Valantinas, Clinic of Gastroenterology, Nephrourology and Surgery, Institute of Clinical Medicine, Vilnius University, Vilnius 01513, Lithuania
Kotryna Sedleckaite, Vilnius University, Faculty of Medicine, Vilnius 01513, Lithuania
Juozas Jarasunas, Department of Radiology, Nuclear Medicine and Medical Physics, Institute of Clinical Medicine, Vilnius University, Vilnius 01513, Lithuania
Tomas Strainys, Clinic of Anesthesiology and Intensive Care Institute of Clinical Medicine, Vilnius University, Vilnius 01513, Lithuania
Valentina Liakina, Department of Chemistry and Bioengineering, Faculty of Fundamental Science, Vilnius Gediminas Technical University, Vilnius 10223, Lithuania
Author contributions: Strainiene S, Sedleckaite K, Jarasunas J, and Strainys T performed the patient’s data extraction; Strainiene S, Sedleckaite K, Jarasunas J, and Strainys T wrote the original manuscript and reviewed the literature; Savlan I was the gastroenterologist who followed-up the patient; Jarasunas J was the radiologist in this case and selected the radiological images; Stanaitis J was the endoscopist who performed most of the procedures; Savlan I, Liakina V, and Stundiene I reviewed and edited the manuscript; Stanaitis J, and Valantinas J revised the manuscript for important intellectual content; All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sandra Strainiene, MD, Doctor, Clinic of Gastroenterology, Nephrourology and Surgery, Institute of Clinical Medicine, Vilnius University, 3 Universiteto Street, Vilnius 01513, Lithuania. sandra.strainiene@santa.lt
Received: March 29, 2021
Peer-review started: March 29, 2021
First decision: April 28, 2021
Revised: April 30, 2021
Accepted: May 20, 2021
Article in press: May 20, 2021
Published online: July 26, 2021
Processing time: 113 Days and 23.7 Hours
Core Tip

Core Tip: Biliary inflammatory myofibroblastic tumor (IMT) is a rare, idiopathic, usually benign, mass-forming disease with myofibroblastic proliferation and the varying amount of inflammatory cells that can occur in almost every organ. IMTs of the biliary ducts are an uncommon cause of obstructive jaundice. The clinical and radiological presentation usually mimics cholangiocarcinoma (Klatskin tumor). However, histological examination shows no malignancy. We present a rare, difficult to diagnose and treat biliary IMT, which was unresponsive to the pharmacological treatment and complicated by recurrent infections and disease progression. The global experience towards diagnosing and treating this disease is limited and based mostly on clinical practice experience.