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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2021; 9(21): 5999-6004
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.5999
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.5999
Minimal deviation adenocarcinoma with elevated CA19-9: A case report
Yan Dong, Department of Clinical Medicine, Jining Medical University, Jining 272000, Shandong Province, China
Ying Lv, Department of Radiology, The Affiliated Hospital of Jining Medical University, Jining 272000, Shandong Province, China
Jing Guo, Department of Pathology, The Affiliated Hospital of Jining Medical University, Jining 272000, Shandong Province, China
Lin Sun, Department of Obstetrics and Gynecology, The Affiliated Hospital of Jining Medical University, Jining 272000, Shandong Province, China
Author contributions: Dong Y drafted, reviewed, and revised the manuscript; Sun L was the primary physicians during the patient’s inpatient stay; Lv Y and Guo J provided the images; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lin Sun, MD, Chief Doctor, Department of Obstetrics and Gynecology, The Affiliated Hospital of Jining Medical University, No. 89 Guhuai Road, Jining 272000, Shandong Province, China. dyan0304@163.com
Received: January 28, 2021
Peer-review started: January 28, 2021
First decision: April 25, 2021
Revised: May 7, 2021
Accepted: May 24, 2021
Article in press: May 24, 2021
Published online: July 26, 2021
Peer-review started: January 28, 2021
First decision: April 25, 2021
Revised: May 7, 2021
Accepted: May 24, 2021
Article in press: May 24, 2021
Published online: July 26, 2021
Core Tip
Core Tip: Minimal deviation adenocarcinomas of the uterine cervix are mucinous adenocarcinomas not related to human papillomavirus. They are relatively rare, with atypical clinical presentation, low positive rate under cytology and pathological biopsy, high rate of misdiagnosis, high aggressiveness, and tendency to spread easily during the early stage. The methylation test also improves the specificity and sensitivity of early diagnosis of minimal deviation adenocarcinoma of the cervix.