Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2021; 9(21): 5932-5942
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.5932
Fatigue prevalence in men treated for prostate cancer: A systematic review and meta-analysis
Yu-Hong Luo, Yan-Wei Yang, Chang-Fu Wu, Chao Wang, Wen-Juan Li, Hong-Chen Zhang
Yu-Hong Luo, Hong-Chen Zhang, School of Nursing, Lanzhou University, Lanzhou 730000, Gansu Province, China
Yan-Wei Yang, Department of Stomatology, The 940th Hospital of Joint Logistic Support Force of the Chinese People’s Liberation Army, Lanzhou 730050, Gansu Province, China
Chang-Fu Wu, The First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China
Chao Wang, School of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
Wen-Juan Li, Department of Respiratory and Critical Care, Henan Provincial Hospital, Zhengzhou 450003, Henan Province, China
Author contributions: Luo YH and Yang YW contributed equally to this work; Luo YH and Zhang HC contributed to the design; Wang C and Wu CF completed the data collection; Yang YW and Li WJ provided statistical support; Yang YW and Luo YH provided the analysis; Zhang HC, Luo YH and Yang YW contributed to the manuscript preparation.
Supported by National Natural Science Foundation of China, No. 81701029.
Conflict-of-interest statement: The authors declared no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Hong-Chen Zhang, MD, Lecturer, School of Nursing, Lanzhou University, No. 28 Yanxi Road, Chengguan District, Lanzhou 730000, Gansu Province, China.
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: April 29, 2021
Revised: May 8, 2021
Accepted: May 27, 2021
Article in press: May 27, 2021
Published online: July 26, 2021
Core Tip

Core Tip: This study was a systematic review conducted to determine the prevalence of cancer-related fatigue in patients with prostate cancer. Compared with other types of cancer, little is known about the prevalence of prostate cancer treatment-related fatigue. In this study, we reviewed the data in 14 papers (4736 patients) and found that the pooled prevalence of cancer treatment-related fatigue was 40%. Interestingly, the prevalence of cancer-related fatigue was associated with the type of treatment that the patients received; those undergoing radical prostatectomy had the lowest prevalence of fatigue.