Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2021; 9(21): 5794-5803
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.5794
Therapeutic plasma exchange for hyperlipidemic pancreatitis: Current evidence and unmet needs
Can-Bin Zheng, Zi-Hui Zheng, Yong-Ping Zheng
Can-Bin Zheng, Department of Endocrine and Metabolic Disease, Shantou Central Hospital, Shantou 515031, Guangdong Province, China
Zi-Hui Zheng, Nursing College, Guangdong Pharmaceutical University, Guangzhou 510000, Guangdong Province, China
Yong-Ping Zheng, Department of Gastroenterology, Shantou Central Hospital, Shantou 515031, Guangdong Province, China
Author contributions: Zheng CB wrote the paper; Zheng ZH and Zheng YP collected the data.
Conflict-of-interest statement: All authors declare there is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Yong-Ping Zheng, MD, Chief Doctor, Department of Gastroenterology, Shantou Central Hospital, No. 114 Waima Road, Shantou 515031, Guangdong Province, China.
Received: March 12, 2021
Peer-review started: March 12, 2021
First decision: April 13, 2021
Revised: April 24, 2021
Accepted: May 26, 2021
Article in press: May 26, 2021
Published online: July 26, 2021
Core Tip

Core Tip: Prevalence of hyperlipidemic acute pancreatitis has greatly increased and has become the most common cause of acute pancreatitis not due to gallstones or alcohol. Although therapeutic plasmapheresis has emerged as an effective modality in rapidly reducing serum triglyceride levels and has been used for hyperlipidemic acute pancreatitis clinically, the exact role of therapeutic plasmapheresis in the disease course is unclear and remains poorly evaluated. We herein outline the current evidence and discuss the future research directions.