Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2021; 9(20): 5568-5574
Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5568
Hemoglobin Fukuoka caused unexpected hemoglobin A1c results: A case report
Xue-Ping Lin, Qiu-Rong Yuan, Shi-Qiong Niu, Xi Jiang, Zhi-Kun Wu, Zhao-Fan Luo
Xue-Ping Lin, Qiu-Rong Yuan, Shi-Qiong Niu, Xi Jiang, Zhi-Kun Wu, Zhao-Fan Luo, Department of Clinical Medical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, Guangdong Province, China
Author contributions: Lin XP encountered the case while working on the manuscript, reviewed the literature, and participated in drafting the manuscript; Yuan QR and Niu SQ reviewed the literature and participated in drafting the manuscript; Jiang X and Wu ZK participated in image processing and analysis; Luo ZF revised the manuscript for important intellectual content; all authors approved the final version of the manuscript as submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhao-Fan Luo, PhD, Professor, Department of Clinical Medical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Guangming District, Shenzhen 518107, Guangdong Province, China. luozhaofan@qq.com
Received: December 11, 2020
Peer-review started: December 11, 2020
First decision: April 4, 2021
Revised: April 14, 2021
Accepted: May 20, 2021
Article in press: May 20, 2021
Published online: July 16, 2021
Core Tip

Core Tip: Hemoglobin A1c (HbA1c) is an indicator of diabetes diagnosis and blood glucose monitoring. Therefore, the accuracy of HbA1c results is of great significance to clinical diagnosis and treatment. This case had an abnormal HbA1c result and traced back to a rare hemoglobin variant. Hemoglobin variants are one of the important factors affecting the accuracy of HbA1c results. In this case, different methods were used to detect HbA1c, which can provide reference evidence for subsequent cases and reduce false results reports.