Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2021; 9(20): 5526-5534
Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5526
Duplication of 19q (13.2-13.31) associated with comitant esotropia: A case report
Yue-Lan Feng, Ning-Dong Li
Yue-Lan Feng, Ning-Dong Li, Department of Ophthalmology, National Center for Children's Health, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China
Yue-Lan Feng, Department of Ophthalmology, First Hospital Affiliated to Baotou Medical College, Baotou 014010, Inner Mongolia Autonomous Region, China
Author contributions: Feng YL and Li ND conducted a clinical examination of the patient and drafted the manuscript; All authors read and approved the final manuscript.
Informed consent statement: Consent was obtained from relatives of the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ning-Dong Li, MD, Doctor, Department of Ophthalmology, National Center for Children's Health, Beijing Children’s Hospital, Capital Medical University, No. 56 South Lishi Road, Xicheng District, Beijing 100045, China. lnd30@163.com
Received: November 4, 2020
Peer-review started: November 4, 2020
First decision: December 21, 2020
Revised: December 23, 2020
Accepted: March 11, 2021
Article in press: March 11, 2021
Published online: July 16, 2021
Core Tip

Core Tip: The pure duplication of 19q is a rare chromosome abnormality that may affect a number of genes. Patients with 19q abnormality show a complicated syndrome such as developmental delay, dysmorphic features, and clinical nurse specialist malformations. To date, only 8 patients with partial trisomy of 19q have been reported. Here, we describe a girl with pure duplication of 19q, who was diagnosed with congenital esotropia, microcephaly, and gallbladder agenesis.