Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2021; 9(20): 5470-5478
Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5470
Prognostic factors and its predictive value in patients with metastatic spinal cancer
Qing-Peng Gao, Da-Zhi Yang, Zheng-Bin Yuan, Yu-Xia Guo
Qing-Peng Gao, Department of Spine Surgery, The Second Clinical Medical College of Jinan University, Shenzhen 518020, Guangdong Province, China
Da-Zhi Yang, Zheng-Bin Yuan, Department of Spine Surgery, Shenzhen People’s Hospital, 2nd Clinical Medical College of Jinan University, Shenzhen 518020, Guangdong Province, China
Yu-Xia Guo, Department of Gynecology, Shenzhen People’s Hospital, 2nd Clinical Medical College of Jinan University, Shenzhen 518020, Guangdong Province, China
Author contributions: Gao QP, Yang DZ, Yuan ZB, and Guo YX contributed to the writing and revising of the manuscript; and all authors proofed and confirmed the revised manuscript.
Institutional review board statement: The study was reviewed and approved by the Shenzhen People’s Hospital Institutional Review Board.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: This is no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Xia Guo, MD, Associate Chief Physician, Department of Gynecology, Shenzhen People’s Hospital, 2nd Clinical Medical College of Jinan University, No. 1017 Dongmen North Road, Luohu District, Shenzhen 518020, Guangdong Province, China. yxguomedicine@163.com
Received: April 1, 2021
Peer-review started: April 1, 2021
First decision: April 13, 2021
Revised: April 25, 2021
Accepted: April 26, 2021
Article in press: April 26, 2021
Published online: July 16, 2021
Processing time: 96 Days and 23 Hours
Core Tip

Core Tip: Early detection and prompt management usually ensure a better prognosis for cancer patients. It is important to examine the prognostic factors that influence the prognosis of patients with metastatic spine tumors in order to determine the optimal treatment strategy. The present study showed that age, comorbidity of metastasis from elsewhere, therapies, number of spinal tumors, patient attitude toward tumors and Karnofsky performance score significantly influenced prognosis of patients with metastatic spine tumors. Moreover, Frankel spinal cord injury functional classification scale score, metastatic spinal cord compression, spinal instability neoplastic score and revised Tokuhashi score were important factors influencing the prognosis of this disease and the treatment selection.