Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2021; 9(20): 5462-5469
Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5462
Effects of angiotensin receptor blockers and angiotensin-converting enzyme inhibitors on COVID-19
Xiao-Long Li, Tao Li, Qi-Cong Du, Li Yang, Kun-Lun He
Xiao-Long Li, Department of Diagnostic Radiology, PLA General Hospital, Beijing 100853, China
Tao Li, Li Yang, Department of Radiology, The First Medical Center of PLA General Hospital, Beijing 100853, China
Qi-Cong Du, Department of Diagnostic Radiology, The First Medical Center of PLA General Hospital, Beijing 100853, China
Kun-Lun He, Translational Medical Research Center, Key Laboratory of Ministry of Industry and Information Technology of Biomedical Engineering and Translational Medicine, Medical Innovation Research Division of Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Li XL, Li T and Du QC contribute equally to this article and should be considered as co-first authors; Li XL and Du QC performed the operation; Li XL and He KL designed this retrospective study; Du QC and Yang L wrote this paper; Li T was responsible for sorting the data.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Huoshenshan Hospital, Wuhan, China (Approval No. HSSLL019).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kun-Lun He, MD, Chief Physician, Translational Medical Research Center, Key Laboratory of Ministry of Industry and Information Technology of Biomedical Engineering and Translational Medicine, Medical Innovation Research Division of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. kunlunhe@plagh.org
Received: April 6, 2021
Peer-review started: April 6, 2021
First decision: April 28, 2021
Revised: April 30, 2021
Accepted: May 24, 2021
Article in press: May 24, 2021
Published online: July 16, 2021
Core Tip

Core Tip: We investigated whether the use of renin-angiotensin-aldosterone system inhibitors by coronavirus disease 2019 patients with hypertension aggravated the severity of pneumonia by comparing the differences in computed tomography images.