Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2021; 9(19): 5203-5210
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5203
Delayed retroperitoneal hemorrhage during extracorporeal membrane oxygenation in COVID-19 patients: A case report and literature review
Jing-Chen Zhang, Tong Li
Jing-Chen Zhang, Tong Li, Department of Critical Care Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Author contributions: Zhang JC generated the idea of the case report and was the consultant in charge of patients; Zhang JC reviewed the case notes of patients and wrote the original draft of the case presentation; Li T significantly revised the original draft and added the conclusions and references; All authors contributed to the final version of the manuscript.
Informed consent statement: The patient gave consent for publication of this case report and images.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tong Li, MD, MSc, Research Associate, Department of Critical Care Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. drli@zju.edu.cn
Received: January 27, 2021
Peer-review started: January 27, 2021
First decision: February 11, 2021
Revised: February 21, 2021
Accepted: May 15, 2021
Article in press: May 15, 2021
Published online: July 6, 2021
Processing time: 147 Days and 16.9 Hours
Core Tip

Core Tip: Retroperitoneal hemorrhage (RPH) is a rare complication during the application of extracorporeal membrane oxygenation (ECMO). Corona virus disease-19 (COVID-19) is often accompanied by coagulation disorders, and the use of heparin in patients with severe COVID-19 patients during ECMO treatment increases the bleeding risk. Three COVID-19 patients who experienced RPH during ECMO treatment were investigated. Nursing operations, lifting, and excessive examination are the main reasons for the occurrence of RPH. RPH should be promptly excluded in patients with decreased blood pressure, hemoglobin, and ECMO flow rate to avoid dangerous complications.