Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2021; 9(19): 5007-5018
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5007
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5007
Insights into the virologic and immunologic features of SARS-COV-2
Ceylan Polat, Koray Ergunay, Department of Medical Microbiology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey
Author contributions: Polat C and Ergunay K equally contributed to collect data and to write the paper; both authors read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that there is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ceylan Polat, PhD, Assistant Professor, Department of Medical Microbiology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara 06100, Turkey. ceylan.polat@hacettepe.edu.tr
Received: March 16, 2021
Peer-review started: March 16, 2021
First decision: May 1, 2021
Revised: May 3, 2021
Accepted: May 24, 2021
Article in press: May 24, 2021
Published online: July 6, 2021
Peer-review started: March 16, 2021
First decision: May 1, 2021
Revised: May 3, 2021
Accepted: May 24, 2021
Article in press: May 24, 2021
Published online: July 6, 2021
Core Tip
Core Tip: Robust cellular and humoral responses are elicited in immunocompetent individuals with severe acute respiratory syndrome coronavirus 2 infection that remain detectable for several months following exposure. A balanced T cell response and neutralizing antibodies in circulation and mucosal surfaces are pivotal in controlling virus infection and for protection. Particular impairments in innate and adaptive immune responses are associated with pathogenesis and severe disease.