Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2021; 9(18): 4741-4747
Published online Jun 26, 2021. doi: 10.12998/wjcc.v9.i18.4741
Primary mesonephric adenocarcinoma of the fallopian tube: A case report
Chuan Xie, Yang-Mei Shen, Qiu-He Chen, Ce Bian
Chuan Xie, Qiu-He Chen, Ce Bian, Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Yang-Mei Shen, Department of Pathology, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Xie C performed the data collection and manuscript writing; Shen YM performed the data collection and figure preparation; Chen QH performed the figure preparation; Bian C performed the manuscript writing and editing; all authors have read and approved the manuscript.
Informed consent statement: Written consent to publish this information was obtained from the patient.
Conflict-of-interest statement: The authors declare no conflict of interest/competing interests in publishing the present manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ce Bian, MD, PhD, Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, No. 20 Section Three, South Renmin Road, Chengdu 610041, Sichuan Province, China. terrybian@163.com
Received: October 27, 2020
Peer-review started: October 27, 2020
First decision: January 17, 2021
Revised: April 21, 2021
Accepted: April 29, 2021
Article in press: April 29, 2021
Published online: June 26, 2021
Core Tip

Core Tip: We present the first case of primary mesonephric adenocarcinoma (MNAC) deriving from the fallopian tube without sign of relapse or metastasis after second excision of recurrent lesions until now, which demonstrated a satisfactory response to combination chemotherapy of gemcitabine and carboplatin. MNAC originating from the fallopian tube can be very aggressive, even at early stage. Because of its sensitivity to the chemotherapy regimen, it is reasonable that combination chemotherapy of gemcitabine and carboplatin plays an important role in treatment of recurrent MNAC deriving from the fallopian tube. However, further research is needed to determine the effectiveness of this chemotherapy regimen and provide better therapeutic regimen.