Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2021; 9(17): 4285-4293
Published online Jun 16, 2021. doi: 10.12998/wjcc.v9.i17.4285
Rosai-Dorfman disease with lung involvement in a 10-year-old patient: A case report
Guo-Jing Wu, Bo-Bo Li, Ren-Liang Zhu, Chao-Jie Yang, Wen-Yong Chen
Guo-Jing Wu, Wen-Yong Chen, The Second Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China
Guo-Jing Wu, Bo-Bo Li, Ren-Liang Zhu, Chao-Jie Yang, Wen-Yong Chen, Department of Otolaryngology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Author contributions: Li BB, Zhu RL, and Chen WY discovered this case; Wu GJ and Chen WY contributed to manuscript drafting; Li BB and Yang CJ collected the data; Wu GJ, Zhu RL, and Chen WY followed the patient; all authors had read and approved the final manuscript.
Supported by Discipline Upgrading Program of Guangzhou University of Traditional Chinese Medicine: Clinical and Basic Research on Prevention and Treatment of Otorhinolaryngology with the Combination of Traditional Chinese and Western Medicine, No. A3-0402-20-415-107 (Undetermined).
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no funding, financial relationships, or conflicts of interest to disclose.
CARE Checklist (2016) statement: The guidelines of the “CARE Checklist–2016: Information for writing a case report” have been adopted.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen-Yong Chen, MS, Doctor, Department of Otolaryngology, Guangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, No. 111 Dade Road, Yuexiu District, Guangzhou 510120, Guangdong Province, China. gzdoctorcwy@126.com
Received: January 15, 2021
Peer-review started: January 15, 2021
First decision: February 11, 2021
Revised: February 22, 2021
Accepted: March 29, 2021
Article in press: March 29, 2021
Published online: June 16, 2021
Processing time: 131 Days and 4.8 Hours
Core Tip

Core Tip: In this paper we report a 10-year-old girl characterized by enlarged left cervical lymph nodes. Imaging suggested a malignant tumor with pulmonary metastasis, and Rosai-Dorfman disease (RDD) was finally diagnosed by pathological and immunohistochemical methods. This case suggests that attention should be paid to RDD in the differential diagnosis of cervical masses. Second, the diagnosis of RDD should not rely solely on imaging examination, and different diagnostic methods should be used. Moreover, although rare, there is a situation that RDD involves the lungs. Finally, the treatment of RDD needs to be constantly explored and the treatment plan should be adjusted according to the follow-up results.