Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2021; 9(16): 3858-3868
Published online Jun 6, 2021. doi: 10.12998/wjcc.v9.i16.3858
Management and outcomes of surgical patients with intestinal Behçet’s disease and Crohn’s disease in southwest China
Li Zeng, Wen-Jian Meng, Zhong-Hui Wen, Yi-Long Chen, Yu-Fang Wang, Cheng-Wei Tang
Li Zeng, Zhong-Hui Wen, Yu-Fang Wang, Cheng-Wei Tang, Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Wen-Jian Meng, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Yi-Long Chen, West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Zeng L collected the data, performed the research, and wrote the paper; Tang CW and Wang YF designed the research and supervised and reviewed the report; Meng WJ and Wen ZH designed the research and contributed to the analysis; Chen YL performed and verified statistical analysis.
Supported by National Natural Science Foundation of China, No. 81270447.
Institutional review board statement: Ethical approval was obtained from the Biomedical Ethics Committee of West China Hospital, Sichuan University.
Informed consent statement: The patients provide signed informed consent to the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Fang Wang, MD, Chief Doctor, Department of Gastroenterology, West China Hospital, Sichuan University, 37 Guo Xue Road, Wuhou District, Chengdu 610041, Sichuan Province, China. wangyufang04@126.com
Received: November 30, 2020
Peer-review started: November 30, 2020
First decision: February 23, 2021
Revised: March 1, 2021
Accepted: April 6, 2021
Article in press: April 6, 2021
Published online: June 6, 2021
Core Tip

Core Tip: This real-world study was designed to identify effective postoperative treatment for patients with gastrointestinal involvement in Behçet's disease (GIBD) from the experience of Crohn’s disease (CD). Indication for first surgery was often acute gastrointestinal complications for GIBD patients, compared with patients with CD frequently undergoing purposed elective surgeries. Although no statistically significant difference was observed, patients with GIBD suffered more and earlier recurrences and reoperations than patients with CD. Awareness should be raised about the emergency condition of GIBD because it is more likely to be discounted than CD in clinics. Furthermore, they may require more aggressive treatment for more severe disease process postoperatively, like biological agents.