Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2021; 9(15): 3765-3772
Published online May 26, 2021. doi: 10.12998/wjcc.v9.i15.3765
De novo multiple primary carcinomas in a patient after liver transplantation: A case report
Wei Rao, Fu-Guo Liu, Yue-Ping Jiang, Man Xie
Wei Rao, Division of Hepatology, Liver Disease Center, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Wei Rao, Department of Organ Transplantation, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Fu-Guo Liu, Yue-Ping Jiang, Man Xie, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Author contributions: Rao W contributed to data curation and analysis, and original manuscript drafting; Liu FG and Jiang YP contributed to manuscript writing, review, and editing; Xie M contributed to funding acquisition, conceptualization, supervision, and manuscript writing, review, and editing.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors of this manuscript have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Man Xie, MD, PhD, Assistant Professor, Associate Chief Physician, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 59 Hai'er Road, Laoshan District, Qingdao 266000, Shandong Province, China. xieman1123@126.com
Received: January 9, 2021
Peer-review started: January 9, 2021
First decision: February 12, 2021
Revised: February 15, 2021
Accepted: March 8, 2021
Article in press: March 8, 2021
Published online: May 26, 2021
Core Tip

Core Tip: Few papers have reported de novo multiple primary carcinomas (MPCs) after liver transplantation (LT) yet. Herein, we retrospectively analyzed an MPC case with gastric cancer and lung cancer after LT. Forty-one months after LT, the patient underwent radical distal gastrectomy for a de novo intramucosal signet ring cell carcinoma in the stomach. Two months later, the patient underwent thoracoscopic wedge resection of the right lower lobe of the right lung for the de novo lung cancer. The patient has survived till now with stable function of the graft. Early diagnosis and early treatment of de novo MPCs are the keys to improving the survival rate and quality of life of LT recipients with de novo MPCs.