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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2021; 9(12): 2930-2936
Published online Apr 26, 2021. doi: 10.12998/wjcc.v9.i12.2930
Published online Apr 26, 2021. doi: 10.12998/wjcc.v9.i12.2930
Sclerosing polycystic adenosis of the submandibular gland: Two case reports
Leng Wu, Chuan-Yu Hu, Chun-Ming Huang, Department of Stomatology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Ying Wang, Department of Pathology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Author contributions: Wu L and Wang Y collected, analyzed, and interpreted data and wrote the manuscript; Huang CM and Hu CY collected, analyzed, and interpreted data and critically reviewed the manuscript; All authors approved the final version of the manuscript.
Supported by National Natural Science Foundation of China , No. 82002893 .
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Ming Huang, MD, PhD, Attending Doctor, Department of Stomatology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Qiaokou District, Wuhan 430000, Hubei Province, China. huangchunming89@whu.edu.cn
Received: January 9, 2021
Peer-review started: January 10, 2021
First decision: January 24, 2021
Revised: February 3, 2021
Accepted: February 24, 2021
Article in press: February 24, 2021
Published online: April 26, 2021
Peer-review started: January 10, 2021
First decision: January 24, 2021
Revised: February 3, 2021
Accepted: February 24, 2021
Article in press: February 24, 2021
Published online: April 26, 2021
Core Tip
Core Tip: Sclerosing polycystic adenosis (SPA) is a rare disease of the salivary gland. To the best of our knowledge, only 5 cases of SPA in the submandibular gland have been reported. Here, we present two new cases of SPA involving the submandibular gland. Even though SPA has a good prognosis after adequate surgery, atypical lesions may occur from mild dysplasia to carcinoma in situ. To date, there have been no reports of recurrence, distant metastases, or mortality associated with SPA in the submandibular gland. Clinicians and pathologists should be familiar with the characteristics of this disease to avoid misdiagnosis and overtreatment.