Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2021; 9(12): 2838-2844
Published online Apr 26, 2021. doi: 10.12998/wjcc.v9.i12.2838
Intramuscular hematoma in rhabdomyolysis patients treated with low-molecular-weight heparin: Report of two cases
Shi-Yang Yuan, Kai-Fan Xie, Jian Yang
Shi-Yang Yuan, Jian Yang, Department of Critical Care Medicine, Nanping First Hospital Affiliated to Fujian Medical University, Nanping 353000, Fujian Province, China
Kai-Fan Xie, Department of Respiratory Medicine, 907 Hospital of the Joint Logistics Team, Nanping 353000, Fujian Province, China
Author contributions: Yuan SY was the patients’ neurosurgeon, reviewed the literature, and contributed to manuscript drafting; Xie KF reviewed the literature and contributed to manuscript drafting; Yang J was responsible for the revision of the manuscript for important intellectual content; all authors provided final approval of the version to be submitted.
Supported by Natural Science Foundation of Fujian Province of China, No. 2020J011312.
Informed consent statement: Written informed consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have nothing to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Yang, MSc, Chief Doctor, Department of Critical Care Medicine, Nanping First Hospital Affiliated to Fujian Medical University, No. 317 Zhongshan Road, Yanping District, Nanping 353000, Fujian Province, China. doctoryj@163.com
Received: November 23, 2020
Peer-review started: November 23, 2020
First decision: January 7, 2021
Revised: January 16, 2021
Accepted: February 22, 2021
Article in press: February 22, 2021
Published online: April 26, 2021
Processing time: 141 Days and 2 Hours
Core Tip

Core Tip: We report two patients with rhabdomyolysis caused by heat stroke who developed an intermuscular hematoma during prophylactic anticoagulation therapy. We used heparinized continuous renal replacement therapy, and the patients’ conditions gradually stabilized after a few days. However, in the use of anticoagulants to prevent deep vein thrombosis, the two patients had a progressive decline in hemoglobin. After comprehensive examination, common blood loss was excluded, such as gastrointestinal bleeding, retroperitoneal hematoma, and pleural and abdominal hematoma, and the diagnosis of intramuscular hematoma of the lumbosacral region and buttock was finally confirmed.