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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2020; 8(24): 6380-6388
Published online Dec 26, 2020. doi: 10.12998/wjcc.v8.i24.6380
Published online Dec 26, 2020. doi: 10.12998/wjcc.v8.i24.6380
SRY-negative 45,X/46,XY adult male with complete masculinization and infertility: A case report and review of literature
Yan-Hua Wu, Hui Bao, Ying-Jian Chen, Department of Laboratory Medicine, The 960th Hospital of The PLA Joint Logistics Support Force, Jinan 250031, Shandong Province, China
Ke-Na Sun, Department of Medical Laboratory, Weifang Medical University, Weifang 261053, Shandong Province, China
Author contributions: Chen YJ designed the study and revised the manuscript; Wu YH performed data acquisition, analysis, and interpretation and wrote the manuscript; Sun KN and Bao H performed the experiments; All authors issued final approval of the submitted version of the manuscript.
Informed consent statement: All study participants, or their legal guardians, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying-Jian Chen, PhD, Chief Doctor, Professor, Department of Laboratory Medicine, The 960th Hospital of The PLA Joint Logistics Support Force, No. 25 Shifan Road, Tianqiao District, Jinan 250031, Shandong Province, China. yjqchen@126.com
Received: August 6, 2020
Peer-review started: August 6, 2020
First decision: September 13, 2020
Revised: September 28, 2020
Accepted: October 13, 2020
Article in press: October 13, 2020
Published online: December 26, 2020
Processing time: 135 Days and 7.6 Hours
Peer-review started: August 6, 2020
First decision: September 13, 2020
Revised: September 28, 2020
Accepted: October 13, 2020
Article in press: October 13, 2020
Published online: December 26, 2020
Processing time: 135 Days and 7.6 Hours
Core Tip
Core Tip: A rare chromosomal abnormality is 45,X/46,XY mosaicism. Here, we describe the diagnosis of a rare case of a 45,X/46,XY SRY-negative man with complete virilization and infertility as the main anomaly.