Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2020; 8(23): 6122-6129
Published online Dec 6, 2020. doi: 10.12998/wjcc.v8.i23.6122
Neuronal intranuclear inclusion disease mimicking acute cerebellitis: A case report
Jiao-Jiao Guo, Zi-Yi Wang, Meng Wang, Zong-Zhi Jiang, Xue-Fan Yu
Jiao-Jiao Guo, Zi-Yi Wang, Meng Wang, Zong-Zhi Jiang, Xue-Fan Yu, Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Jiang ZZ collected the clinical data; Wang M reviewed and searched the literature; Guo JJ and Wang ZY designed and drafted the manuscript; Yu XF gave critical comments; Guo JJ and Wang ZY contributed equally to this study; all authors read and approved the final manuscript.
Supported by Project of Science and Technology Department of Jilin Province, China, No. 20190303181 SF.
Informed consent statement: Informed written consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Fan Yu, MD, Doctor, Department of Neurology and Neuroscience center, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. xuefan@jlu.edu.cn
Received: June 19, 2020
Peer-review started: June 19, 2020
First decision: September 23, 2020
Revised: October 2, 2020
Accepted: November 2, 2020
Article in press: November 2, 2020
Published online: December 6, 2020
Processing time: 165 Days and 5.8 Hours
Core Tip

Core Tip: While the clinical manifestations of neuronal intranuclear inclusion disease (NIID) are highly variable, a patient with NIID whose primary symptoms indicated acute cerebellitis has hitherto never been reported. We document the rare case of a patient with NIID who did not receive any special treatment and eventually recovered completely. Our report provides evidence of acute cerebellar ataxia and bilateral symmetric cerebellar high-intensity signal as clinical and imaging features of NIID, respectively.