Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2020; 8(22): 5690-5700
Published online Nov 26, 2020. doi: 10.12998/wjcc.v8.i22.5690
Endoscopic resection of benign esophageal schwannoma: Three case reports and review of literature
Bin Li, Xue Wang, Wen-Lu Zou, Shu-Xia Yu, Yong Chen, Hong-Wei Xu
Bin Li, Shu-Xia Yu, Yong Chen, Hong-Wei Xu, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250012, Shangdong Province, China
Xue Wang, Department of Gastroenterology,Dezhou People’s Hospital, Dezhou 253014, Shangdong Province, China
Wen-Lu Zou, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shangdong Province, China
Author contributions: Li B and Wang X conceived the study idea and design; Wang X and Zou WL performed the patient data collection; Li B and Xu HW drafted the article; Yu SX and Chen Y revised the manuscript; Chen Y supervised the study; All authors have read and approved the manuscript.
Supported by The Shandong Key Research and Development Program, No. 2016GSF201004; and The Jinan Science and Technology Plan Project, No. 201705055.
Informed consent statement: All data published here are under consent for publication. Written informed consent was obtained from all individual participants included in the study. The written consent mentioned here is for the publication of patient/clinical details.
Conflict-of-interest statement: All other authors have nothing to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hong-Wei Xu, MD, Professor, Chief Doctor, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwuweiqi Road, Jinan 250012, Shangdong Province, China. xhongwei808@163.com
Received: June 23, 2020
Peer-review started: June 23, 2020
First decision: July 24, 2020
Revised: August 15, 2020
Accepted: October 19, 2020
Article in press: October 19, 2020
Published online: November 26, 2020
Core Tip

Core Tip: Most esophageal schwannomas are rare submucosal lesions, and malignant esophageal schwannoma has been reported. We summarize three cases of esophageal schwannoma with successful endoscopic resection. They were misdiagnosed as leiomyoma or cystic solid tumors based on endoscopic ultrasound before surgery. Small lesions in a suitable location can be removed endoscopically by experienced endoscopists using endoscopic submucosal excision or submucosal tunneling endoscopic resection. For larger lesions (> 3 cm), especially tumors with cystic degeneration, endoscopic treatment may not be suitable. For such lesions, robot-assisted thoracoscopic excision or endoscopic treatment combined with video-assisted thoracoscopic surgery may be a better option.