Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2020; 8(21): 5250-5283
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5250
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5250
Cardiovascular impact of COVID-19 with a focus on children: A systematic review
Moises Rodriguez-Gonzalez, Pediatric Cardiology Division, Puerta del Mar University Hospital, Cadiz 11009, Spain
Moises Rodriguez-Gonzalez, Ana Castellano-Martinez, Biomedical Research and Innovation Institute of Cadiz, Puerta del Mar University Hospital, Cadiz 11009, Spain
Ana Castellano-Martinez, Pediatric Nephrology Division, Puerta del Mar University Hospital, Cadiz 11009, Spain
Helena Maria Cascales-Poyatos, Pediatrics Division, Motril-San Antonio Primary Care Center, Motril 18600, Spain
Alvaro Antonio Perez-Reviriego, Pediatrics Division, UGC Pediatria AG Sur Granada, Santa Ana Hospital, Motril 18600, Spain
Author contributions: All the authors participated in the search of evidence and revision of the articles selected; Rodriguez-Gonzalez M designed the review, made the statistical analysis and wrote the first draft of the manuscript; Perez-Reviriego AA, Castellano-Martinez A and Cascales-Poyatos HM revised the first draft of the manuscript; Perez-Reviriego AA and Cascales-Poyatos HM summarized data on the tables of the final manuscript; Castellano-Martinez A made the figure of the final manuscript.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
PRISMA 2009 Checklist statement: A PRISMA checklist was used to guide the development of the systematic review.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Moises Rodriguez-Gonzalez, MD, Doctor, Pediatric Cardiology Division, Puerta del Mar University Hospital, 21, Ana de Viya Avenue, Cadiz 11009, Spain. doctormoisesrodriguez@gmail.com
Received: September 1, 2020
Peer-review started: September 1, 2020
First decision: September 13, 2020
Revised: September 16, 2020
Accepted: October 13, 2020
Article in press: October 13, 2020
Published online: November 6, 2020
Peer-review started: September 1, 2020
First decision: September 13, 2020
Revised: September 16, 2020
Accepted: October 13, 2020
Article in press: October 13, 2020
Published online: November 6, 2020
Core Tip
Core Tip: Cardiovascular involvement has emerged as a remarkable risk-factor for poor outcomes of primary respiratory diseases such as coronavirus disease-2019 (COVID-19). Nevertheless, the body of evidence of cardiac complications in pediatric COVID-19 is still scarce to extract definitive conclusions about the adequate management for these patients. This review establishes a perspective on how COVID-19 impacts on the heart of both previously healthy children and those with pre-existing heart diseases, and how to take care of them during the current pandemic emergency.