Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2020; 8(20): 4876-4882
Published online Oct 26, 2020. doi: 10.12998/wjcc.v8.i20.4876
Paliperidone palmitate-induced facial angioedema: A case report
Maytinee Srifuengfung, Thanisorn Sukakul, Chanika Liangcheep, Natee Viravan
Maytinee Srifuengfung, Chanika Liangcheep, Natee Viravan, Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Thanisorn Sukakul, Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Author contributions: Srifuengfung M designed the report; Liangcheep C was the patient’s physician, collected the patient’s data, and reviewed the literature; Sukakul T interpreted the clinical data and image findings; Srifuengfung M, Sukakul T, and Viravan N reviewed the literature and wrote the manuscript; all authors were responsible for the revision of the manuscript; and all authors approved the final version for publication.
Informed consent statement: Informed written consent was obtained from the patient’s legally authorized representative for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Natee Viravan, FRCP, MD, Doctor, Lecturer, Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok 10700, Thailand. natee.vir@mahidol.ac.th
Received: June 6, 2020
Peer-review started: June 6, 2020
First decision: September 13, 2020
Revised: September 15, 2020
Accepted: September 25, 2020
Article in press: September 25, 2020
Published online: October 26, 2020
Processing time: 141 Days and 18.2 Hours
Core Tip

Core Tip: Paliperidone palmitate-induced angioedema can present with insidious onset, intermittent, facial edema which may be overlooked. Previous reports show that paliperidone-induced angioedema, which may cause life-threatening laryngeal edema, may be dose-related. This report raises awareness of this rare, adverse effect, angioedema. Close monitoring of patients should be performed when they are administered paliperidone palmitate, especially psychiatric patients who are unable to detect their illness.