Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2020; 8(16): 3583-3590
Published online Aug 26, 2020. doi: 10.12998/wjcc.v8.i16.3583
Published online Aug 26, 2020. doi: 10.12998/wjcc.v8.i16.3583
Multifocal neuroendocrine cell hyperplasia accompanied by tumorlet formation and pulmonary sclerosing pneumocytoma: A case report
Xiao-Yu Han, Yuan-Yuan Wang, Hong-Quan Wei, Department of Pathology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Guang-Zhao Yang, Jian Wang, Yu-Zhu Jia, Wei-Qun Ao, Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Author contributions: Han XY, Jia YZ, Wei HQ, Wang J, and Wang YY were responsible for the collection and analysis of the patient’s data; Ao WQ and Han XY drafted the manuscript; Ao WQ and Yang GZ performed the manuscript editing and revising.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wei-Qun Ao, MD, Doctor, Radiologist, Department of Radiology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou 310012, Zhejiang Province, China. 78123858@qq.com
Received: February 18, 2020
Peer-review started: February 18, 2020
First decision: July 4, 2020
Revised: July 6, 2020
Accepted: July 16, 2020
Article in press: July 16, 2020
Published online: August 26, 2020
Peer-review started: February 18, 2020
First decision: July 4, 2020
Revised: July 6, 2020
Accepted: July 16, 2020
Article in press: July 16, 2020
Published online: August 26, 2020
Core Tip
Core tip: Pulmonary tumorlets are nodular hyperplastic neuroendocrine cells that extend beyond the basement membrane. They often coexist with other lung diseases such as fibrosis and bronchiectasis, but rarely accompanied by pulmonary sclerosing pneumocytoma. This paper reports a rare clinical case of bronchiectasis complicated with multifocal nodular hyperplastic neuroendocrine cell hyperplasia, tumorlet, and pulmonary sclerosing pneumocytoma. The patient was followed after computed tomography scanning and received surgical resection. We observed the progression of the tumor that has not yet been reported, which can be of great value in the diagnosis of the disease.