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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2020; 8(14): 2950-2958
Published online Jul 26, 2020. doi: 10.12998/wjcc.v8.i14.2950
Published online Jul 26, 2020. doi: 10.12998/wjcc.v8.i14.2950
Clinical characteristics of patients with COVID-19 presenting with gastrointestinal symptoms as initial symptoms: Retrospective case series
Tuo-Yun Yang, Yuan-Chao Li, Qing-Qing Dai, Xue-Song Jiang, Shu Zuo, Liu Jia, Jun-Bo Zheng, Hong-Liang Wang, Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Si-Cong Wang, Department of Critical Care Medicine, the Cancer Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, China
Author contributions: Yang TY and Wang HL designed this research study; Yang TY, Li YC, Dai QQ, Wang SC, and Jiang XS performed the research; Jia L, Zheng JB, and Zuo S analyzed the data; Yang TY, Dai QQ, and Zheng JB wrote the manuscript; all authors have read and approve the final manuscript.
Supported by China International Medical Foundation , No. Z-2018-35-1902 .
Institutional review board statement: Due to the special circumstances, this study was authorized by the Ethics Commission of Second Affiliated Hospital of Harbin Medical University (KY2020-007) and orally authorized by the Wuhan Union Hospital.
Informed consent statement: Written informed consent was waived by the Ethics Commission for emerging infectious diseases.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hong-Liang Wang, MD, Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, No. 246, Xuefu Road, Nangang District, Harbin 150086, Heilongjiang Province, China. icuwanghongliang@163.com
Received: May 21, 2020
Peer-review started: May 21, 2020
First decision: June 4, 2020
Revised: June 14, 2020
Accepted: July 1, 2020
Article in press: July 1, 2020
Published online: July 26, 2020
Processing time: 64 Days and 8.1 Hours
Peer-review started: May 21, 2020
First decision: June 4, 2020
Revised: June 14, 2020
Accepted: July 1, 2020
Article in press: July 1, 2020
Published online: July 26, 2020
Processing time: 64 Days and 8.1 Hours
Core Tip
Core tip: The objective of this retrospective case series was to characterize the clinical features of coronavirus-infected patients with gastrointestinal symptoms as initial symptoms. The clinical investigation of disease onset was underestimated, especially due to the neglection of cases presenting with gastrointestinal symptoms. We aimed to address this issue and provide an insight into the different initial symptoms between the pulmonary symptoms and gastrointestinal symptoms. Coronavirus disease 2019 patients presenting with gastrointestinal symptoms as initial symptoms need more days of viral shedding and hospitalization than the patients presenting with pulmonary symptoms.