Jin Q, Zhao ZH, Luo Q, Zhao Q, Yan L, Zhang Y, Li X, Yang T, Zeng QX, Xiong CM, Liu ZH. Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: State of the art. World J Clin Cases 2020; 8(13): 2679-2702 [PMID: 32742980 DOI: 10.12998/wjcc.v8.i13.2679]
Corresponding Author of This Article
Zhi-Hong Liu, MD, PhD, Doctor, Professor, State Key Laboratory of Cardiovascular Disease, Center for Pulmonary Vascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Xicheng District, Beijing 100037, China. zhihongliufuwai@163.com
Research Domain of This Article
Respiratory System
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 6, 2020; 8(13): 2679-2702 Published online Jul 6, 2020. doi: 10.12998/wjcc.v8.i13.2679
Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: State of the art
Qi Jin, Zhi-Hui Zhao, Qin Luo, Qing Zhao, Lu Yan, Yi Zhang, Xin Li, Tao Yang, Qi-Xian Zeng, Chang-Ming Xiong, Zhi-Hong Liu
Qi Jin, Zhi-Hui Zhao, Qin Luo, Qing Zhao, Lu Yan, Yi Zhang, Xin Li, Tao Yang, Qi-Xian Zeng, Chang-Ming Xiong, Zhi-Hong Liu, State Key Laboratory of Cardiovascular Disease, Center for Pulmonary Vascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Author contributions: Jin Q, Zhao ZH and Luo Q contributed equally to the conception, literature review and manuscript drafting, and should be considered as co-first authors; Zhao Q, Yan L, Zhang Y, Li X, Yang T, Zeng QX and Xiong CM collected the data and revised the literature, and Liu ZH conceived and revised the paper. All authors read and approved the final manuscript.
Supported bythe National Precision Medical Research Program of China, No. 2016YFC0905602.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhi-Hong Liu, MD, PhD, Doctor, Professor, State Key Laboratory of Cardiovascular Disease, Center for Pulmonary Vascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Xicheng District, Beijing 100037, China. zhihongliufuwai@163.com
Received: March 22, 2020 Peer-review started: March 22, 2020 First decision: April 22, 2020 Revised: May 28, 2020 Accepted: June 10, 2020 Article in press: June 10, 2020 Published online: July 6, 2020 Processing time: 106 Days and 13.1 Hours
Core Tip
Core tip: Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious chronic disease with a poor prognosis if left untreated. Pulmonary endarterectomy (PEA) is the only curable treatment of choice for certain CTEPH patients with proximal vessel lesions. Balloon pulmonary angioplasty (BPA) is a promising alternative interventional option for patients with CTEPH, especially those with distal lesions or residual/recurrent pulmonary hypertension after PEA. Herein, we summarize the pathophysiology of CTEPH, the history and development of BPA, therapeutic principles, indications and contraindications, interventional procedures, imaging modalities, efficacy and prognosis, complications and management, bridging and hybrid therapies, ongoing clinical trials and future prospects.
