Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2020; 8(12): 2662-2666
Published online Jun 26, 2020. doi: 10.12998/wjcc.v8.i12.2662
Diffuse alveolar hemorrhage with histopathologic manifestations of pulmonary capillaritis: Three case reports
Jun Xie, Ying-Yue Zhao, Jing Liu, Guang-Min Nong
Jun Xie, Ying-Yue Zhao, Jing Liu, Guang-Min Nong, Department of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Xie J, Zhao YY, and Nong GM conceptualized and designed the study; Xie J and Zhao YY drafted the initial manuscript; Liu J designed the data collection instruments, collected the data, and carried out the initial analyses; Xie J, Zhao YY, and Liu J reviewed and revised the manuscript; Nong GM coordinated and supervised the data collection, and critically reviewed the manuscript for important intellectual content; All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.
Informed consent statement: Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no potential conflicts of interest to disclose.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Guang-Min Nong, MD, Professor, Department of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. ngm8525@163.com
Received: February 26, 2020
Peer-review started: February 26, 2020
First decision: April 21, 2020
Revised: April 28, 2020
Accepted: May 21, 2020
Article in press: May 21, 2020
Published online: June 26, 2020
Processing time: 119 Days and 0.3 Hours
Core Tip

Core tip: This is a report of three children with diffuse alveolar hemorrhage and pulmonary capillaritis who presented with recurrent hemoptysis: One was antinuclear antibody-positive and two were antibody-negative. The condition can be controlled in patients using glucocorticoid alone or combination of immunosuppressant treatment.