Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2019; 7(7): 891-897
Published online Apr 6, 2019. doi: 10.12998/wjcc.v7.i7.891
Villous adenoma coexistent with focal well-differentiated adenocarcinoma of female urethral orifice: A case report and review of literature
Lu-Feng Qin, Ye Liang, Xiao-Ming Xing, Hui Wu, Xue-Cheng Yang, Hai-Tao Niu
Lu-Feng Qin, Hui Wu, Department of Medicine, Qingdao University, Qingdao 266003, Shandong Province, China
Lu-Feng Qin, Hui Wu, Xue-Cheng Yang, Hai-Tao Niu, Department of Urology, Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Ye Liang, Hai-Tao Niu, Key Laboratory of Urinary System Diseases, Qingdao 266003, Shandong Province, China
Xiao-Ming Xing, Department of Pathology, Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Author contributions: Qin LF, Liang Y, Wu H, Yang XC, Xing XM, and Niu HT collected the case data; Qin LF wrote the manuscript; Niu HT revised the manuscript.
Informed consent statement: All patients completed informed consent forms.
Conflict-of-interest statement: None of the authors have a conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hai-Tao Niu, MD, Doctor, Professor, Surgeon, Surgical Oncologist, Department of Urology, Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266003, Shandong Province, China. niuhttg@163.com
Telephone: +86-532-82911953
Received: December 3, 2018
Peer-review started: December 6, 2018
First decision: December 15, 2018
Revised: January 2, 2019
Accepted: January 26, 2019
Article in press: January 26, 2019
Published online: April 6, 2019
Processing time: 123 Days and 19.6 Hours
Core Tip

Core tip: Villous adenoma coexisting with adenocarcinoma of the urinary system is uncommon. Differential diagnosis from villous adenoma of the digestive tract is difficult. We present a case of villous adenoma coexisting with adenocarcinoma of the female urethral orifice and provide an accurate method to differentiate villous adenomas of the urinary and digestive tracts.