Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2019; 7(20): 3364-3371
Published online Oct 26, 2019. doi: 10.12998/wjcc.v7.i20.3364
Synchronous quadruple primary malignancies of the cervix, endometrium, ovary, and stomach in a single patient: A case report and review of literature
Dan-Dan Wang, Qing Yang
Dan-Dan Wang, Qing Yang, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Author contributions: Wang DD was responsible for the data collection and drafting of the manuscript; Yang Q was responsible for critical revision of the manuscript; all authors read and approved the final manuscript.
Supported by Grants from the Outstanding Scientific Fund of Shengjing Hospital, No. 201704; the Support Program for Youth Backbone of China Medical University, No. QGZD2018062.
Informed consent statement: Informed consent to publish was obtained from the patient.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2013), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Qing Yang, MD, PhD, Professor, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. yangqing_sj@126.com
Telephone: +86-24-23892617
Received: June 1, 2019
Peer-review started: June 4, 2019
First decision: August 1, 2019
Revised: September 5, 2019
Accepted: September 11, 2019
Article in press: September 11, 2019
Published online: October 26, 2019
Core Tip

Core tip: Multiple primary malignancies (MPMs) are rare and most involve two sites. Herein we report an exceptional case of quadruple primary malignancies in a single patient, including endocervical adenocarcinoma, endometrial endometrioid adenocarcinoma, endometrioid ovarian carcinoma, and gastric adenocarcinoma. The nature of MPMs remains unknown, and further research into the etiology and mechanisms of MPMs is warranted.