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World J Clin Cases. Jun 6, 2019; 7(11): 1242-1252
Published online Jun 6, 2019. doi: 10.12998/wjcc.v7.i11.1242
Radiation therapy for extrahepatic bile duct cancer: Current evidences and future perspectives
Taeryool Koo, Hae Jin Park, Kyubo Kim
Taeryool Koo, Department of Radiation Oncology, Hallym University Sacred Heart Hospital, Anyang 14068, South Korea
Hae Jin Park, Department of Radiation Oncology, Hanyang University College of Medicine, Seoul 04763, South Korea
Kyubo Kim, Department of Radiation Oncology, Ewha Womans University College of Medicine, Seoul 07985, South Korea
Author contributions: Kim K concepted and designed the study; Koo T and Park HJ reviewed and analyzed literature, and drafted the manuscript. All authors contributed to critical revision and editing, and approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Kyubo Kim, MD, PhD, Associate Professor, Department of Radiation Oncology, Ewha Womans University College of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu, Seoul 07985, South Korea. kyubokim.ro@gmail.com
Telephone: +82-2-2650-5334 Fax: +82-2-2654-0363
Received: February 21, 2019
Peer-review started: February 22, 2019
First decision: March 29, 2019
Revised: April 2, 2019
Accepted: April 18, 2019
Article in press: April 19, 2019
Published online: June 6, 2019
Processing time: 105 Days and 17.7 Hours
Core Tip

Core tips: Radiotherapy has been administered for extrahepatic bile duct cancer patients in adjuvant, definitive, or palliative settings. The evidence in support of radiotherapy is derived from retrospective studies because there is a lack of randomized controlled trials. This review aimed to summarize contemporary series involving radiotherapy treatment for extrahepatic bile duct cancer. These data and findings were then used to propose strategies for generating robust evidence for or against the use of radiotherapy for this disease.