Observational Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2019; 7(10): 1122-1132
Published online May 26, 2019. doi: 10.12998/wjcc.v7.i10.1122
Diagnostic value of two dimensional shear wave elastography combined with texture analysis in early liver fibrosis
Zhao-Cheng Jian, Jin-Feng Long, Yu-Jiang Liu, Xiang-Dong Hu, Ji-Bin Liu, Xian-Quan Shi, Wei-Sheng Li, Lin-Xue Qian
Zhao-Cheng Jian, Yu-Jiang Liu, Xiang-Dong Hu, Xian-Quan Shi, Wei-Sheng Li, Lin-Xue Qian, Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Zhao-Cheng Jian, Jin-Feng Long, Medical Imaging Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China
Ji-Bin Liu, Institute of Ultrasound, Thomas Jefferson University Hospital, Philadelphia, PA 19107, United States
Author contributions: All authors helped to perform the research; Jian ZC manuscript writing, performing procedures and data analysis; Long JF contribution to writing the manuscript, performing experiments, and data analysis; Liu YJ and Hu XD contribution to performing experiments; Liu JB contribution to writing the manuscript; Shi XQ and Li WS contribution to data analysis; Qian LX manuscript writing, drafting conception and design, performing experiments, and data analysis.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Beijing Friendship Hospital, Capital Medical University.
Informed consent statement: Patient's informed consent was obtained before the study,though the clinical data used in this study were anonymous.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Lin-Xue Qian, MD, Chief Doctor, Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, No. 95 Yongan Road, Xicheng District, Beijing 100050, China. qianlinxue2002@163.com
Telephone: +86-13562645007 Fax: +86-10-63138576
Received: February 2, 2019
Peer-review started: February 2, 2019
First decision: March 10, 2019
Revised: March 19, 2019
Accepted: April 8, 2019
Article in press: April 9, 2019
Published online: May 26, 2019
Core Tip

Core tip: This study explored the diagnostic value of texture analysis in early liver fibrosis in patients with chronic hepatitis B on the basis of two dimensional shear wave elastography. It demonstrated that texture analysis was capable of diagnosing liver fibrosis, combined diagnosis had obvious advantages in early liver fibrosis, and the liver fibrosis stage might be related to the spatial heterogeneity of hepatic tissue hardness distribution.