Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2024; 12(8): 1442-1447
Published online Mar 16, 2024. doi: 10.12998/wjcc.v12.i8.1442
Development of immature ovarian teratoma after mature teratoma in a girl with familial ovarian teratoma: A case report
U Chul Ju, Woo Dae Kang, Seok Mo Kim
U Chul Ju, Woo Dae Kang, Seok Mo Kim, Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju 61469, South Korea
Co-first authors: U Chul Ju and Woo Dae Kang.
Author contributions: Ju UC, Kang WD and Kim SM designed the research study; Ju UC and Kang WD performed the research and analyzed the data; Kim SM provided help and advice on the data analyzation; Ju UC and Kang WD wrote the manuscript; All authors contributed to editorial changes in the manuscript; All authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient and her parents for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Seok Mo Kim, MD, PhD, Professor, Department of Obstetrics and Gynecology, Chonnam National University Medical School, 8 Hakdong, Dong-gu, Gwangju 61469, South Korea. ddiamo94@gmail.com
Received: November 13, 2023
Peer-review started: November 13, 2023
First decision: January 9, 2024
Revised: January 15, 2024
Accepted: February 18, 2024
Article in press: February 18, 2024
Published online: March 16, 2024
Processing time: 119 Days and 21.7 Hours
Core Tip

Core Tip: This report describes a unique case of an adolescent woman with familial ovarian teratoma that was initially diagnosed as mature ovarian teratoma and later recurred and identified as immature ovarian teratoma during follow-up. Our case highlights the importance of genetic counseling, screening, and close surveillance in families with a predisposition to ovarian teratomas. Collaborative efforts between oncologists, geneticists, and researchers are necessary to determine the underlying mechanisms and develop targeted interventions for individuals at high risk of immature teratomas.