Tricuspid mass-curious case of Li-Fraumeni syndrome: A letter to the editor

doi:10.12998/wjcc.v12.i33.6644

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Nov 26, 2024 (publication date) through Sep 27, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Clin Cases. Nov 26, 2024; 12(33): 6644-6646
Published online Nov 26, 2024. doi: 10.12998/wjcc.v12.i33.6644

Tricuspid mass-curious case of Li-Fraumeni syndrome: A letter to the editor

Mohammad S Al-Haggar, Zahraa A Abdelmoneim

Mohammad S Al-Haggar, Department of Pediatrics and Genetics, Mansoura University Children's Hospital, Mansoura 35516, Egypt

Zahraa A Abdelmoneim, Department of Pediatrics, Genetic Unit, Mansoura University Children Hospital, Mansoura 35516, Egypt

Author contributions: Al-Haggar MS revised the manuscript; Abdelmoneim ZA wrote the manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Zahraa A Abdelmoneim, MD, Lecturer, Department of Pediatrics, Genetic Unit, Mansoura University Children Hospital, EL Gomhoria Street, Mansoura 35516, Egypt. hzahraa211@gmail.com

Received: March 6, 2024
Revised: August 3, 2024
Accepted: September 19, 2024
Published online: November 26, 2024
Processing time: 204 Days and 22.3 Hours

Core Tip

Core Tip: Li-Fraumeni syndrome (LFS) is an inherited propensity to various distinct, frequently uncommon malignancies. Pediatric and adolescent age groups are more likely to acquire many malignancies, including soft-tissue and bone tumors, breast cancer, central nervous system cancers, adrenocortical carcinoma, and blood cancers. LFS individuals may also develop various types of cancer, including gastrointestinal, lung, kidney, thyroid, and skin cancers, as well as those affecting the gonadal organs. An accurate diagnosis of LFS is critical for afflicted families to receive appropriate genetic counseling and be monitored for early cancer detection.