Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2024; 12(22): 4940-4946
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.4940
Serum inflammatory markers in children with Mycoplasma pneumoniae pneumonia and their predictive value for mycoplasma severity
Li-Ping Wang, Zhong-Hua Hu, Jun-Sheng Jiang, Jie Jin
Li-Ping Wang, Zhong-Hua Hu, Jun-Sheng Jiang, Department of Pediatrics, The First People's Hospital of Linping District, Hangzhou 310000, Zhejiang Province, China
Jie Jin, Department of Pediatrics, Changzhou Children Hospital, Changzhou 213100, Jiangsu Province, China
Author contributions: Wang LP wrote the main manuscript text; Hu ZH prepared the related review; Jiang JS was responsible for supporting and supervising; Jin J prepared the figure and Table; All authors reviewed the manuscript.
Institutional review board statement: The study was approved by the First People's Hospital of Linping District Ethics Commit (No: linping2023044).
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All authors declare that there is no conflict of interest.
Data sharing statement: Not applicable.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Jin, MD, Chief, Department of Pediatrics, Changzhou Children Hospital, Tianning District Zhonghu Strict, Changzhou 213100, Jiangsu Province, China. 3355144716@qq.com
Received: March 8, 2024
Revised: May 26, 2024
Accepted: June 14, 2024
Published online: August 6, 2024
Processing time: 115 Days and 21.1 Hours
Core Tip

Core Tip: This study highlights the significant correlation between elevated serum inflammatory markers and severity of Mycoplasma pneumoniae pneumonia (MPP) in children. Key markers such as C-reactive protein, procalcitonin, erythrocyte sedimentation rate, lactic dehydrogenase, D-dimer, and cytokines [interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor] serve as valuable predictors for severe MPP, aiding in early diagnosis and improved prognosis.