Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2024; 12(21): 4536-4542
Published online Jul 26, 2024. doi: 10.12998/wjcc.v12.i21.4536
Correlation between type 2 diabetes mellitus remission and intrapancreatic fat deposition
Jiang Liu, Yue Luo, Yin-Rong Zhu, Zu-Tao Wu, Yan Hou, Yu-Jie Xu, Li Li, Cun-Wen Ma
Jiang Liu, Yin-Rong Zhu, Zu-Tao Wu, Yan Hou, Yu-Jie Xu, Li Li, Division of Endocrinology, Wenshan Hospital Affiliated to Kunming University of Science and Technology, Wenshan 663000, Yunnan Province, China
Yue Luo, Cun-Wen Ma, Department of Radiological Medicine, Wenshan Hospital Affiliated to Kunming University of Science and Technology, Wenshan 663000, Yunnan Province, China
Author contributions: Liu J and Ma CW contributed to conception, design, data analysis, and manuscript drafting and editing; Liu J, Luo Y, Zhu YR, Wu ZT, Hou Y and Ma CW contributed to collection, assembly of data and revised the manuscript; Liu J, Xu YJ and Li L contributed to conception, resources, and manuscript review and editing; all authors have read and approved the final manuscript.
Supported by Kunming University of Science and Technology Joint School Medicine Project, No. KUST-WS2022002Z.
Institutional review board statement: This study was approved by the Ethic Committee of Wenshan Hospital, Kunming University of Science and Technology (Approval No. WYLS2022005).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: Dr. Ma has nothing to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cun-Wen Ma, MM, Chief Physician, Department of Radiological Medicine, Wenshan Hospital Affiliated to Kunming University of Science and Technology, No. 228 Kaihua East Road, Wenshan 663000, Yunnan Province, China. mcw20241201@163.com
Received: March 21, 2024
Revised: May 9, 2024
Accepted: June 13, 2024
Published online: July 26, 2024
Processing time: 100 Days and 16.7 Hours
Core Tip

Core Tip: This study on 80 patients with type 2 diabetes mellitus (T2DM) with abdominal obesity confirmed that T2DM remission and intrapancreatic fat deposition were negatively correlated, as well as the benefits of liraglutide in glycemic control and pancreatic function repair in T2DM. Our findings are of great significance for advancing research on diabetes mellitus and fat and building appropriate treatment models for patients with T2DM. However, there are limitations such as insufficient sample size and lack of basic experiments.