Non-surgical treatment of diabetic foot ulcers on the dorsum of the foot with polydeoxyribonucleotide injection: Two case reports

doi:10.12998/wjcc.v12.i20.4446

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Jul 16, 2024 (publication date) through Jun 30, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Clin Cases. Jul 16, 2024; 12(20): 4446-4451
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4446

Non-surgical treatment of diabetic foot ulcers on the dorsum of the foot with polydeoxyribonucleotide injection: Two case reports

Yooseok Ha, Jeong-Hee Kim, Jiyoung Kim, Hyeokjae Kwon

Yooseok Ha, Jeong-Hee Kim, Hyeokjae Kwon, Department of Plastic and Reconstructive Surgery, Chungnam National University Hospital, Daejeon 35015, South Korea

Jiyoung Kim, College of Nursing, Woosuk University, Wanju-gun 55338, South Korea

Author contributions: Kwon H performed the research; Ha Y and Kim JH wrote the manuscript (original draft); Kim J and Kwon H wrote the manuscript (reviewing and editing); All authors have read and approved the final manuscript.

Informed consent statement: Informed consent was obtained from all patients for being included in the study.

Conflict-of-interest statement: The authors report no relevant conflicts of interest for this article.

CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Hyeokjae Kwon, MD, PhD, Assistant Professor, Surgeon, Department of Plastic and Reconstructive Surgery, Chungnam National University Hospital, 282 Munhwa-ro Jung-gu Daejeon, Daejeon 35015, South Korea. kwon.hyeokjae@cnuh.co.kr

Received: April 10, 2024
Revised: May 15, 2024
Accepted: May 29, 2024
Published online: July 16, 2024
Processing time: 80 Days and 13.1 Hours

Core Tip

Core Tip: If a diabetic foot wound of Wager grade II or less is located on the dorsum of the foot and is not amenable to surgical treatment, polydeoxyribonucleotide injection combined with a minimally invasive treatment of debridement under local anesthesia may help wound healing in patients who are not amenable to surgical treatment.